Research Sector News Therapies — 30 March 2016

Mental illnesses, like depression, are largely triggered by life events not genetics, and more funding should be allocated to find their true cause


Mental illness is largely caused by social crises such as unemployment or childhood abuse and too much money is spent researching genetic and biological factors, psychologists have warned.

Over the past decade funding bodies like the Medical Research Council (MRC) have spent hundreds of millions on determining the biology of mental illness.

But while there has been some success in uncovering genes which make people more susceptible to various disorders, specialists say that the true causes of depression and anxiety are from life events and environment, and research should be directed towards understanding the everyday triggers.

Peter Kinderman, Professor of Clinical Psychology at the University of Liverpool, told BBC Radio 4’s Today programme: “Of course every single action, every emotion I’ve ever had involves the brain, so to have a piece of scientific research telling us that the brain is involved in responding emotionally to events doesn’t really advance our understanding very much.

“And yet it detracts from the fact that when unemployment rates go up in a particular locality you get a measurable number of suicides.

“It detracts from the idea that trauma in childhood is a very very powerful predictor of serious problems like experiencing psychotic events in adult life, so of course the brain is involved and of course genes are involved, but not very much, and an excessive focus on those issues takes us away from these very important social factors”

Almost half of adults will suffer from a mental health condition at some stage in their life and more than a third of GP surgery consultations are due to mental problems.

One in four people have been diagnosed with some type of mental health problem – most commonly depression. In addition, 18 per cent said they had suffered from such illness, but never been diagnosed.

The UK now has the seventh highest prescribing rate for antidepressants in the Western world, separate figures show, with around four million Britons taking them each year – twice as many as a decade ago.

Yet the MRC spends just three per cent of its research budget funding studies into mental illness, most of which goes towards genetics or neuroscience.

Prof Richard Bentall, also of Liverpool University added: “It’s a tragedy actually. The UK Medical Research Council is one of the biggest funders of medical research in the UK but if you look at the things that they fund, by far the majority are things like brain scanners or gene sequencing machines, almost none of it is going towards understanding psychological mechanisms or social circumstances by which these problems develop.guy-781482_1280

“It is impossible to get funding to look at these kind of things.”

The MRC said it was currently refreshing its strategic plan and was hoping to increase the amount of money allocated the mental health studies.

“I think it has been a longstanding debate, the issue of nature versus nurture, and the MRC needs to make sure it funds the research which his going to have the most impact wherever it comes from,” said Dr Rob Buckle, Head of Regenerative medicine at MRC.

“The issue here is that mental health is a very complex issue and the fundamental thing is to get a better understanding of the causes and progression of mental illness.

“We would like to spend more of our budget on mental health research and we totally accept this is interdisciplinary and involves neuroscientists and psychiatrists and social scientists and we do fund work around social impacts on mental health.”

However other scientists argued that finding out the root causes of mental illness could prove beneficial to the greatest numbers of people.

Dr Jeff Barrett, who is working on uncovering the genes behind mental illness at the Wellcome Trust’s Sanger Institute said: “If we understand the fundamental biology of the disease it might be relevant in developing new ideas for therapies that are applicable to a wide range of patients.

“So if by doing studies like this we can strongly implicate one area of biology it gives a new lead for drug companies to try to develop new therapies.”

This article first appeared on ‘The Telegraph UK’ on 28 March 2016.



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MHAA Staff

(3) Readers Comments

  1. I am wondering why the very last part of this article goes back to ‘developing new therapies’ with the help of drug companies. I am training in the field of creative arts therapy, have had severe depression myself, have had the medication, have struggled with debilitating anxiety, and yet it is poetry, the support of those who unconditionally love you, my own faith, and the desire to not be ‘judged’ and ‘labeled’ as weak and defective that have been the driving force of my recovery. I no longer take medication. I am training to become a poetry/creative arts therapist and I have reaffirmed by commitment to fight the stigma associated with mental and emotional anguish because it is mostly, sadly, based on a medical model of diagnosis. Anything less than a holistic view of human suffering WHICH MUST INCLUDE socio-political, cultural and economic forces is a deep and shameful betrayal of what it means to be human and to extend empathy beyond the offering of ‘drugs’ to ease what in many cases is, I believe, existential suffering. I have suffered. I have weaknesses as a human being. But I am not so defective that these external forces can sit by and allow me to suffer, whoever I am, and not be held to account.

  2. The rest of the article…I must say…brought deep healing and affirming to my heart. Thank you!!!!!

  3. My apologies for the passion in my response. It springs from deep deep trauma of the labeling (not from my treating professionals, I have to clarify…) by a culture and a system that perpetuates stigma through language and ironically, through silence… The system and our culture of individualism is what deeply let us down as a community, I believe. Thank you again for posting the article. I was so grateful to discover it.

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